CAS 52232-67-4 Teriparatide acetate Activator Teriparatide

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Common name Teriparatide Acetate English name pTH (1-34) (human) acetate salt
CAS number 52232-67-4
Molecular formula C181H291N55O51S2
Molecular weight 4177.77000
Appearance traits powder
Storage conditions Sealed, store at -20 ºC
Stability No decomposition, no known hazardous reactions if used and stored according to specifications
  Usage: Teriparatide is a PHT activator that stimulates the associated G-protein cyclic monophosphate production. Teriparatide is also known as recombinant human parathyroid hormone (1-34) and it exhibits anabolic effects on bone. Teriparatide is an anti-osteoporotic drug that is clinically used to treat osteoporosis; it does not exhibit anti-resorptive benefit, but stimulates bone formation and increases bone strength. Teriparatide activates the PTH1 receptor. In clinical settings, teriparatide decreases new fracture occurrence and back pain and increases lumbar spinal bone mineral density. In mouse bone marrow stromal cells, teriparatide upregulates expression of osterix and Runx2; in paired animal models, this compound increases osteoblast maturation and improves fracture healing. 证书 包装

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